Christopher L. Keown, PhD
Cognitive Science, UCSD


List of Publications

(*authors contributed equally)

Zhang, Tie-Yuan*, Christopher L. Keown*, Xianglan Wen, Junhao Li, Dulcie A. Vousden, Christoph Anacker, Urvashi Bhattacharyya, et al. 2018. "Environmental Enrichment Increases Transcriptional and Epigenetic Differentiation between Mouse Dorsal and Ventral Dentate Gyrus." Nature Communications 9 (1):298.

Luo, Chongyuan*, Christopher L. Keown*, Laurie Kurihara, Jingtian Zhou, Yupeng He, Junhao Li, Rosa Castanon, et al. 2017. "Single-Cell Methylomes Identify Neuronal Subtypes and Regulatory Elements in Mammalian Cortex." Science 357 (6351): 600–604.

Keown, Christopher L., Joel B. Berletch, Rosa Castanon, Joseph R. Nery, Christine M. Disteche, Joseph R. Ecker, and Eran A. Mukamel. 2017. "Allele-Specific Non-CG DNA Methylation Marks Domains of Active Chromatin in Female Mouse Brain." Proceedings of the National Academy of Sciences of the United States of America, March. doi:10.1073/pnas.1611905114.

Keown, Christopher L., Michael C. Datko, Colleen P. Chen, Jose Omar Maximo, Afrooz Jahedi, and Ralph-Axel Müller. 2017. "Network Organization Is Globally Atypical in Autism: A Graph Theory Study of Intrinsic Functional Connectivity." Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 2 (1). Elsevier: 66–75.

Shen, Mark D., Deana D. Li, Christopher L. Keown, Aaron Lee, Ryan T. Johnson, Kathleen Angkustsiri, Sally J. Rogers, Ralph-Axel Müller, David G. Amaral, and Christine Wu Nordahl. 2016. "Functional Connectivity of the Amygdala Is Disrupted in Preschool-Aged Children With Autism Spectrum Disorder." Journal of the American Academy of Child and Adolescent Psychiatry 55 (9): 817–24.

Chen, Colleen P., Christopher L. Keown, Afrooz Jahedi, Aarti Nair, Mark E. Pflieger, Barbara A. Bailey, and Ralph-Axel Müller. 2015. "Diagnostic Classification of Intrinsic Functional Connectivity Highlights Somatosensory, Default Mode, and Visual Regions in Autism." NeuroImage. Clinical 8 (April): 238–45.

Khan, Amanda J., Aarti Nair, Christopher L. Keown, Michael C. Datko, Alan J. Lincoln, and Ralph-Axel Müller. 2015. "Cerebro-Cerebellar Resting-State Functional Connectivity in Children and Adolescents with Autism Spectrum Disorder." Biological Psychiatry 78 (9): 625–34.

Abbott, Angela E., Aarti Nair, Christopher L. Keown, Michael Datko, Afrooz Jahedi, Inna Fishman, and Ralph-Axel Müller. 2016. "Patterns of Atypical Functional Connectivity and Behavioral Links in Autism Differ Between Default, Salience, and Executive Networks." Cerebral Cortex 26 (10): 4034–45.

So, Alex Yick-Lun, Reeshelle Sookram, Aadel A. Chaudhuri, Aarathi Minisandram, David Cheng, Catherine Xie, Ee Lyn Lim, …, Christopher L. Keown, et al. 2014. "Dual Mechanisms by Which miR-125b Represses IRF4 to Induce Myeloid and B-Cell Leukemias." Blood 124 (9): 1502–12.

Fishman, Inna, Christopher L. Keown, Alan J. Lincoln, Jaime A. Pineda, and Ralph-Axel Müller. 2014. "Atypical Cross Talk between Mentalizing and Mirror Neuron Networks in Autism Spectrum Disorder." JAMA Psychiatry 71 (7): 751–60.

Nair, Aarti*, Christopher L. Keown*, Michael Datko, Patricia Shih, Brandon Keehn, and Ralph-Axel Müller. 2014. "Impact of Methodological Variables on Functional Connectivity Findings in Autism Spectrum Disorders." Human Brain Mapping 35 (8): 4035–48.

Keown, Christopher Lee, Patricia Shih, Aarti Nair, Nick Peterson, Mark Edward Mulvey, and Ralph-Axel Müller. 2013. "Local Functional Overconnectivity in Posterior Brain Regions Is Associated with Symptom Severity in Autism Spectrum Disorders." Cell Reports 5 (3): 567–72.

Maximo, Jose O., Christopher L. Keown, Aarti Nair, and Ralph-Axel Müller. 2013. "Approaches to Local Connectivity in Autism Using Resting State Functional Connectivity MRI." Frontiers in Human Neuroscience 7 (October): 605.

Chen, Colleen Pam, Christopher L. Keown, and Ralph-Axel Müller. 2013. "Towards Understanding Autism Risk Factors: a Classification of Brain Images with Support Vector Machines" International Journal of Semantic Computing 07 (02): 205–13.

Di Martino, A., C-G Yan, Q. Li, E. Denio, F. X. Castellanos, K. Alaerts, J. S. Anderson, …, Christopher L. Keown et al. 2014. "The Autism Brain Imaging Data Exchange: Towards a Large-Scale Evaluation of the Intrinsic Brain Architecture in Autism." Molecular Psychiatry 19 (6): 659–67.

Shih, Patricia, Brandon Keehn, Jessica K. Oram, Kelly M. Leyden, Christopher L. Keown, and Ralph-Axel Müller. 2011. "Functional Differentiation of Posterior Superior Temporal Sulcus in Autism: A Functional Connectivity Magnetic Resonance Imaging Study." Biological Psychiatry 70 (3): 270–77.